Laboratory for Nanoengineered Materials & Biosensing Technologies

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Publications

2018

32. Khandelwal A. V., Singh A., Pal N., Goel  Goel G., Gupta S. ‘AC conductivity of colloidal suspensions’, to be submitted

31. Kalita P. and Gupta S., ‘An ultrasensitive homogeneous agglutination assay for lipopolysachharide detection’, to be submitted

30. Goel M., Singh A., Bhola A. and Gupta S., Size-tunable assembly of gold nanoparticles into conductive films and microwires using AC electrokinetics’, Submitted

29. Manoharan H., Kalita P., Gupta S. and Sai V.V.R., ‘Plasmonic biosensors for bacterial endotoxin detection in C-18 supported U-bent fiber optic probes’, Submitted

28. Dixit A., Goel M. and Gupta S., ‘Optimization of optoelectronically tunable CdTe microwire formation using AC dielectrophoresis’, Submitted

27. Jagtap P., Mishra R., Khanna S., Mittal B., Kumari P., Kashyap H. and Gupta S., ‘Mechanistic evaluation of lipopolysaccharide-alexidine interaction using spectroscopic and in silico approaches‘, ACS Infectious Diseases, 4(11), 1546-1552 (2018)

26. Malik S., Anand S. and Gupta S., A non-invasive platform to estimate fasting blood glucose levels from salivary electrochemical parameters, Healthcare Technology Letters, Accepted

25. Jagtap P.*, Singh R.*, Deepika K., Sritharan V., Gupta S., ‘A flow through assay for rapid, bedside stratification of endotoxemia in critically ill patients: A pilot study‘, Journal of Clinical Microbiology, 56(9), 1-13 (2018) (*Equal contribution)

24. Prasad P., Sachan S., Suman S., Swyambhu G. and Gupta S., ‘Regenerative core-shell nanoparticles probes for simultaneous removal and detection of endotoxins‘, Langmuir, 34, 7396–7403 (2018)

23. Goel M., Verma A. and Gupta S., ‘Electric-field driven capture and detection of live bacterial cells in microarrays‘, Biosensors and Bioelectronics, 11, 159 – 165 (2018)

22. Singh R. and Gupta S., ‘Dual-functionality nanobioconjugates: A new tool for intracellular bacterial targeting in cancer?‘, Therapeutic Delivery, 9, 317-320 (2018)

21.  Pandey V., Gupta S. and Elangovan R. E., ‘Compact 3D printed module for fluorescent and label-free imaging using evanescent excitationMethods and Applications in Fluorescence, 6, 015007 (2018)

2017

20. Kalita P., Bhola A., Goel N., Sritharan V. and Gupta S., ‘Heterogeneous Endotoxin Detection Bioassay using Drug-nanoparticle Bioconjugates: An Optimization StudyMolecular Systems Design and Engineering, 2 , 470-477 (2017)

19. Singh R.*, Patil S.*, Singh N. and Gupta S., ‘Antimicrobial Activity of Polymyxin B Sulfate and Sushi Peptide Nanoparticle Bioconjugates on Gram-negative Bacteria Scientific Reports 7:5792, 1- 10 (2017) (*Equal contribution)

18. Kalita P., Chaturvedula M., Sritharan V. and Gupta S., ‘In vitro Flow-Through Assay for Rapid Detection of Endotoxin in Human SeraNanomedicine: Nanotchnology, Biology, and Medicine, 13, 1483-1490 (2017)

2016

17. Baig M.M., Jain S., Gupta S., Vignesh G., Singh V., Kondraju S. and Gupta S., ‘Engineering Droplet Navigation through Tertiary-Junction Microchannels Microfluidics and Nanofluidics, 20:165 (2016)

16. Jagtap P., Sritharan V. and Gupta S., ‘Nanotheranostic Approaches for the Management of Bloodstream Bacterial Infections Nanomedicine: Nanotchnology, Biology, and Medicine, 13, 329 – 341 (2016)

15. Singh S., Upadhyay M, Pandey V., Gupta S., Perumal V. and Elangovan R., ‘Spot Immunomagnetic Enrichment Device for Rapid Detection of Pathogens in Peripheral Blood‘, Advanced Materials Technologies, 1600101, 1 – 9 (2016)

14. Malik S., Khadgawat R., Anand S. and Gupta S., ‘Non-invasive Detection of Fasting Blood Glucose Level via Electrochemical Measurement of Saliva SpringerPlus 5:701 (2016)

13. S. Singh, M. Upadhyaya, J. Sharma, S. Gupta, V. Perumal, and R. Elangovan, ‘A portable immunomagnetic cell capture system to accelerate culture diagnosis of bacterial infectionsAnalyst 141, 3358-3366 (2016)

12. Pal N., Sharma S. and Gupta S., ‘Sensitive and Rapid Detection of Pathogenic Bacteria in Small Volumes using Impedance Spectroscopy Technique Biosensors and Bioelectronics 77, 270-276 (2016)

2015

11. Kalita P., Dasgupta A., Sritharan V. and Gupta S., ‘Nanoparticle-drug Bioconjugate as Dual Functional Affinity Ligand for Rapid Detection of Endotoxin in Water and SerumAnalytical Chemistry 87, 11007-11012 (2015)

10. Maheshwari G., Mittal M., Sapra S. and Gupta S., ‘Electrically-Driven Assembly of CdTe Quantum Dots into Semiconducting Microwires J. Mater. Chem. C 3, 1645-1648 (2015)

2013

9. Jain S. and Gupta S., ‘Dielectrophoretic Co-Assembly of Binary Colloidal Mixtures in AC Electric FieldsLangmuir 29, 16105-16112 (2013)

2012 and earlier

8. Gupta S., Kilpatrick P.K., Melvin E. and Velev O.D., ‘On-Chip Latex Agglutination Immunoassay Readout by Electrochemical Impedance SpectroscopyLab on a Chip 12, 4279-4286 (2012)

7. Gupta S.*, Andresen H.A.* and Stevens M.M., ‘Kinetic Investigation of Bioresponsive Nanoparticle Assembly as a Function of Ligand DesignNanoscale 3, 383-386 (2011) *Equal contribution

6. Gupta S., Andresen H.A. and Stevens M.M., ‘Single-Step Kinase Inhibitor Screening using a Peptide-Modified Gold Nanoparticle PlatformChemical Communications 47, 2249-2251 (2011) Selected as hot article

5. Gupta S., Andresen H.A., Ghadiali J.E. and Stevens M.M., ‘Kinase-Actuated Immunoaggregation of Peptide-Conjugated Gold NanoparticlesSmall 6, 1509-1513 (2010)

4. Gupta S., Alargova R.G., Kilpatrick P.K. and Velev O.D., ‘Directed Assembly of Live Cells into Functionalized Biomaterials using Dielectrophoresis on a ChipLangmuir 26, 3441-3452 (2010)

3. Velev O.D. and Gupta S., ‘Materials Fabricated by Micro and Nanoparticle Assembly – The Challenging Path from Science to EngineeringAdvanced Materials 21, 1-9 (2009) Among 5 most downloaded papers 5/2009.

2. Gupta S., Alargova R.G., Kilpatrick P.K., and Velev O.D., ‘On-chip Electric Field Driven Assembly of Biocomposites from Live Cells and Functionalized ParticlesSoft Matter 4, 726-730 (2008) Featured on the inside cover.

Soft Matter cover

1. Gupta S., Huda S., Kilpatrick P.K. and Velev O.D., ‘Characterization and Optimization of Gold Nanoparticle Based Silver Enhanced ImmunoassaysAnalytical Chemistry 79, 3810-3820 (2007)

Book Chapter and other reports

*Kalita P., *Dasgupta A. and Gupta S. “Endotoxin Entrapment on Glass via C-18 Self-Assembled Monolayers and Rapid Detection using Drug-Nanoparticle Bioconjugate Probes”, Chap. 13 (133-142), Microbial Toxins: Methods and Protocols (2nd Ed.), MiMB 1600, Springer Protocols (Editor Otto Holst), Humana Press, 2017 (*Equal contribution)

Gupta S. ‘Rapid impedance detection of typhoid-causing bacteria: A step toward a healthier life’ Nano, Bio and Building Technology Newsletter of Foundation for Innovation and Technology Transfer (FITT), IIT Delhi, Vol. 20, No. 2, July 2014

Patents filed

6. Elangovan R., Perumal V., Gupta S., Singh S., “Magnetic capturing of rare cells”, US Patent App. 15/531,401

5. Elangovan R., Perumal V., Gupta S., Singh S., Upadhyay M. “Magnetic enrichment of magnetically marked analytes”, US Patent App. 15/552,248

4. Kalita P., Sritharan V. and Gupta S. “An Assay and Kit for Detection of Endotoxin”, Indian Patent 201611007932 (PCT filed: PCT/IN2016/050397);  US Patent App. 16/082,754 (filing date Sep. 06, 2018);  EU Patent App. 16893365.3 (filing date Oct. 01, 2018)

3. Singh S., Elangovan R. Gupta S. Perumal V., “Portable Device and Disposable Chip for Immunomagnetic Enrichment of Target Biomarkers”, Indian Patent 485/DEL/2015 (PCT filed)

2. Singh S., Elangovan R. Gupta S. Perumal V., “On-chip Immunocapture and Fluorescent Detection of Rare Cells in Large Sample Volume”, Indian Patent 3465/DEL/2014 (PCT filed)

1. Gupta S., Kalita P., Dasgupta A. and Sritharan V., “Platform Device and Method for Detection of Bacterial Lipolysaccharides in Water and Serum”, Indian Patent 3214/DEL/2014

Media coverage

Our article in Biosensors and Bioelectronics  2018 receives media attention: Science Trends

Our recently published work in Sci. Rep. gets media coverage on various platforms: Research Matters; Biovoice News; Down to earth; The India saga; The Hindu; Indian Express; Financial ExpressDaily Pioneer; India Live Today; Science Monitor, Rajya Sabha TV

A short video documentary on our septicemia work recorded by Two Islands Digital (2ID) on behalf of Channel News Asia (CNA) for their segment “Saving Lives”: Click here

Low cost device for sepsis diagnosis“, Identifying Low-cost Medical Device Innovations Transforming Patient Care, Frugal Innovations in Medical Device Industry – Medical Device TechVision Opportunity Engine (TOE), Frost & Sullivan, May 2016

A kit for rapid bedside diagnosis of septicemia” by Science Monitor, Rajya Sabha TV, April 23, 2016

IIT Delhi: Novel device for sepsis diagnosis”, by The Hindu, April 17, 2016

National honours for Global Hospitals”, by Hans India, March 31, 2016

IIT student makes the cheapest sepsis detection kit”, by Dainik Jagran, March 27, 2016

Now, IITs become fertile ground for faculty startups”, by Economic Times, June 23, 2015

India: The fight to become a science superpower” by Nature, May 13, 2015

Open Innovation” by Times of India, April 20, 2015

Faster typhoid diagnosis” by Hindustan Times (New Delhi), April 11, 2015

Test for sepsis diagnosis in development in India” by Medical Device Daily, Feb 2015